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Talhout, Reinskje; Schulz, Thomas; Florek, Ewa; van Benthem, Jan; Wester, Piet; Opperhuizen, Antoon (February 2011). "Hazardous Compounds in Tobacco Smoke". International Journal of Environmental Research and Public Health. 8 (2): 613–628. doi:10.3390/ijerph8020613. ISSN 1661-7827.{{cite journal}}: CS1 maint: unflagged free DOI (link)

"Our list of hazardous smoke components includes all nine components reported in mainstream cigarette smoke that are known human carcinogens (IARC Group I carcinogens), as well as all nine components that are probably carcinogenic to humans (IARC Group 2A carcinogens). In addition, it contains 34 of the 48 components that are possibly carcinogenic to humans (IARC Group 2B carcinogens)."

  • 1Cancer inhalation risk values provide an excess lifetime exposure risk, in this case the human lung cancer risk at a 1 in 100,000 (E-5) level.
Carcinogens or possible carcinogens. Cancer risk value in mg m−3
Smoke component Cancer risk value1 Institute
1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) 1.0E-04 U.S. EPA
1,1-Dimethylhydrazine 2.0E-06 ORNL
1,3-Butadiene 3E-04 U.S. EPA
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TEQ) 2.6E-04 Cal EPA
2-Amino-3-methyl-9H-pyrido[2,3-b]indole (MeAaC) 2.9E-05 Cal EPA
2-Amino-3-methylimidazo[4,5-b]quinoline (IQ) 2.5E-05 Cal EPA
2-Amino-6-methyl[1,2-a:3′,2″-d]imidazole (GLu-P-1) 7.1E-06 Cal EPA
2-Aminodipyrido[1,2-a:3′,2″-d]imidazole (GLu-P-2) 2.5E-05 Cal EPA
2-Aminonaphthalene 2.0E-05 Cal EPA
2-Nitropropane Cal EPA
2-Toluidine 2.0E-04 Cal EPA
3-Amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) 1.4E-06 Cal EPA
3-Amino-1-methyl-5H-pyrido[4,3-b]-indole (Trp-P-2) 1.1E-05 Cal EPA
4-Aminobiphenyl 1.7E-06 Cal EPA
5-Methylchrysene 9.1E-06 Cal EPA
7H-Dibenzo(c,g)carbazole 9.1E-06 Cal EPA
2-Amino-9H-pyrido[2,3-b]indole (AaC) 8.8E-05 Cal EPA
Acetaldehyde 4.5E-03 U.S. EPA
Acetamide 5.0E-04 Cal EPA
Acrylamide 8E-3
Acrylonitrile 1.5E-04 U.S. EPA
Aniline B2—probable human carcinogen U.S. EPA
Arsenic 2.3E-06 U.S. EPA
Benz[a]anthracene 9.1E-05 Cal EPA
Benzene 1.3E-03 U.S. EPA
Benzo[a]pyrene 9.1E-06 Cal EPA
Benzo[j]fluoranthene 9.1E-05 Cal EPA
Beryllium 4.2E-06
Cadmium 5.6E-06 U.S. EPA
Carbazole 1.8E-03 NATA
Chloroform, 4.3E-04 U.S. EPA
Chromium VI 8.3E-07 U.S. EPA
Chrysene 9.1E-04 Cal EPA
Di(2-ethylhexyl) phthalate 4.2E-03 Cal EPA
Dibenzo[a,i]pyrene 9.1E-07 Cal EPA
Dibenzo[a,h]acridine 9.1E-05 Cal EPA
Dibenzo[a,h]anthracene 8.3E-06 Cal EPA
Dibenzo[a,j]acridine 9.1E-05 Cal EPA
Dibenzo[a,h]pyrene 9.1E-07 Cal EPA
Dibenzo[a,l)pyrene 9.1E-07 Cal EPA
Dibenzo[a,e]pyrene 9.1E-06 Cal EPA
Dibenzo[c,g]carbazole 9.1E-06 Cal EPA
Ethyl carbamate 3.5E-05 Cal EPA
Ethylene oxide 1.1E-04 Cal EPA
Ethylenethiourea 7.7E-04 Cal EPA
Formaldehyde 7.7E-04 U.S. EPA
Hydrazine 2.0E-06 U.S. EPA
Indeno(1,2,3-c,d)pyrene 9.1E-05 Cal EPA
Lead 8.3E-04 Cal EPA
N-nitrosodi-n-butylamine (NBUA) 6.3E-06 U.S. EPA
N-nitrosodimethylamine (NDMA) 7.1E-07 U.S. EPA
N-nitrosodiethanolamine 1.3E-05 Cal EPA
N-nitrosodiethylamine 2.3E-07 U.S. EPA
N-nitrosoethylmethylamine 1.6E-06 Cal EPA
N-Nitrosonornicotine (NNN) 2.5E-05 Cal EPA
N-Nitroso-N-propylamine 5.0E-06 Cal EPA
N-nitrosopiperidine 3.7E-06 Cal EPA
N-nitrosopyrrolidine 1.6E-05 U.S. EPA
o-Cresol C- possible human carcinogen U.S. EPA
p-Benzoquinone C- possible human carcinogen U.S. EPA
p-Cresol C- possible human carcinogen U.S. EPA
Polonium-210 925.9 ORNL3
Propylene oxide 2.7E-03 U.S. EPA
Trichloroethylene 82 HC
Vinyl chloride 1.1E-03 U.S. EPA