Body load
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Body load is a term used to describe specific tactile sensations bought on by psychoactive drugs, especially psychedelics. Generally, body load is an unpleasant physical sensation that is difficult to describe either in terms of other sensations or in its specific location. Nausea may be present with, or as a part of, body load. Different drugs may cause different body load sensations which vary in intensity and duration.
In contrast, many drug users, and particularly users of entactogens like MDMA or of certain particular synthetic phenethylamines (most notably the popular 2C-B) and tryptamines, also often report a "body high" or "body rush", which is similar to body load in many respects but is virtually always considered pleasant.