PSME2

PSME2
Identifiers
Aliases	PSME2, PA28B, PA28beta, REGbeta, proteasome activator subunit 2
External IDs	OMIM: 602161; MGI: 1096365; HomoloGene: 86889; GeneCards: PSME2; OMA:PSME2 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q12 Start 24,143,362 bp End 24,147,570 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14 C3|14 28.19 cM Start 55,824,898 bp End 55,828,570 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte duodenum appendix spleen right adrenal cortex mucosa of transverse colon lymph node Pituitary Gland left adrenal gland left adrenal cortex Top expressed in jejunum duodenum ileum colon adrenal gland ovary uterus epiblast spleen white adipose tissue More reference expression data BioGPS More reference expression data
Gene ontology Molecular function endopeptidase activator activity protein binding identical protein binding Cellular component cytoplasm cytosol membrane proteasome activator complex nucleoplasm proteasome complex extracellular exosome Biological process positive regulation of endopeptidase activity regulation of proteasomal protein catabolic process regulation of cellular amino acid metabolic process antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent regulation of mRNA stability positive regulation of canonical Wnt signaling pathway protein polyubiquitination stimulatory C-type lectin receptor signaling pathway tumor necrosis factor-mediated signaling pathway MAPK cascade Fc-epsilon receptor signaling pathway regulation of G1/S transition of mitotic cell cycle NIK/NF-kappaB signaling anaphase-promoting complex-dependent catabolic process T cell receptor signaling pathway negative regulation of canonical Wnt signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process Wnt signaling pathway, planar cell polarity pathway negative regulation of G2/M transition of mitotic cell cycle protein deubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process transmembrane transport regulation of transcription from RNA polymerase II promoter in response to hypoxia post-translational protein modification interleukin-12-mediated signaling pathway regulation of hematopoietic stem cell differentiation interleukin-1-mediated signaling pathway regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5721 19188 Ensembl ENSG00000100911 ENSG00000284889 ENSMUSG00000079197 UniProt Q9UL46 P97372 RefSeq (mRNA) NM_002818 NM_001029855 NM_011190 RefSeq (protein) NP_002809 NP_001268401 Location (UCSC) Chr 14: 24.14 – 24.15 Mb Chr 14: 55.82 – 55.83 Mb PubMed search
Wikidata
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Proteasome (prosome, macropain) activator subunit 2 (PA28 beta), also known as PSME2, is a human gene.