These matrices are useful in polynomial interpolation, since solving an equation for , is equivalent to finding the coefficients of a polynomial that has values at .
The determinant of a square Vandermonde matrix of a dimension can be expressed as follows:
If two or more exponents are equal, the rank of the matrix decreases (if all are distinct, then is of full rank). This problem can alleviated by using a generalisation called confluent Vandermonde matrices, where the k-multiple columns are replaced by: