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NONMEM is a software package developed by Stuart L. Beal and Lewis B. Sheiner in the late 1970s at UCSF for population pharmacokinetic modeling.^[1]^[2]^[3]^[4] Its name is an acronym for non-linear mixed effects modeling.

^ Sheiner, Lewis B.; B. Rosenberg; V.V. Marathe (1977). "Evaluation of Methods for Estimating Population Pharmacokinetic Parameters I. Michaelis-Menten Model: Routine Clinical Pharmacokinetic Data". Journal of Pharmacokinetics and Biopharmaceutics. 5 (5): 445–79. doi:10.1007/BF01061728. PMID 925881.
^ Sheiner, Lewis B.; Stuart L. Beal (1980). "Evaluation of Methods for Estimating Population Pharmacokinetic Parameters I. Michaelis-Menten Model: Routine Clinical Pharmacokinetic Data". Journal of Pharmacokinetics and Biopharmaceutics. 8 (6): 553–71. doi:10.1007/BF01060053.
^ Sheiner, Lewis B.; Stuart L. Beal (1981). "Evaluation of Methods for Estimating Population Pharmacokinetic Parameters II. Biexponential Model and Experimental Pharmacokinetic Data". Journal of Pharmacokinetics and Biopharmaceutics. 9 (5): 635–51. doi:10.1007/BF01061030.
^ Sheiner, Lewis B.; Stuart L. Beal (1983). "Evaluation of Methods for Estimating Population Pharmacokinetic Parameters III. Monoexponential Model: Routine Clinical Pharmacokinetic Data". Journal of Pharmacokinetics and Biopharmaceutics. 11 (3): 303–19. doi:10.1007/BF01061870.

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	'''NONMEM''' is a software package developed by Stuart L. Beal and Lewis B. Sheiner in the late 1970s at [[UCSF]] for [[Pharmacokinetics#Population pharmacokinetics\|population pharmacokinetic modeling]].<ref name="PopPK1" /><ref name="PopPK2" /><ref name="PopPK3" /><ref name="PopPK4" /> Its name is an acronym for non-linear [[Mixed model\|mixed effects modeling]] ~~and has become the "gold standard"{{Citation needed\|date=February 2012}}, both in the pharmaceutical industry and academia~~.		'''NONMEM''' is a software package developed by Stuart L. Beal and Lewis B. Sheiner in the late 1970s at [[UCSF]] for [[Pharmacokinetics#Population pharmacokinetics\|population pharmacokinetic modeling]].<ref name="PopPK1" /><ref name="PopPK2" /><ref name="PopPK3" /><ref name="PopPK4" /> Its name is an acronym for non-linear [[Mixed model\|mixed effects modeling]].

	==References==		==References==