Karyorrhexis: Difference between revisions
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[[Image:nuclear changes.jpg|thumb|right|300px|Morphological characteristics of pyknosis and other forms of nuclear destruction]] |
[[Image:nuclear changes.jpg|thumb|right|300px|Morphological characteristics of pyknosis and other forms of nuclear destruction]] |
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[[Image:Apoptosis.png|thumb|300px|[[Apoptosis]]]] |
[[Image:Apoptosis.png|thumb|300px|[[Apoptosis]]]] |
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'''Karyorrhexis''' (from [[Ancient Greek|Greek]] κάρυον ''karyon'', "kernel, seed or nucleus", and ῥῆξις ''rhexis'', "bursting") is the destructive fragmentation of the [[Cell nucleus|nucleus]] of a dying [[cell (biology)|cell]]<ref name="zamzami">{{cite journal | |
'''Karyorrhexis''' (from [[Ancient Greek|Greek]] κάρυον ''karyon'', "kernel, seed or nucleus", and ῥῆξις ''rhexis'', "bursting") is the destructive fragmentation of the [[Cell nucleus|nucleus]] of a dying [[cell (biology)|cell]]<ref name="zamzami">{{cite journal |vauthors=Zamzami N, Kroemer G | title=Apoptosis: Condensed matter in cell death| journal=Nature| year=1999| volume=401| issue=127 | pmid=10490018 | pages=127–8 | doi=10.1038/43591}}</ref> whereby its chromatin is distributed irregularly throughout the cytoplasm. It is usually preceded by [[pyknosis]] and can occur as a result of either [[programmed cell death]] (apoptosis), senescence, or [[necrosis]]. |
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In [[apoptosis]], the cleavage of [[DNA]] is done by Ca<sup>2+</sup> and Mg<sup>2+</sup> -dependent [[endonucleases]]. |
In [[apoptosis]], the cleavage of [[DNA]] is done by Ca<sup>2+</sup> and Mg<sup>2+</sup> -dependent [[endonucleases]]. |
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[[Category:Cellular senescence]] |
[[Category:Cellular senescence]] |
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[[Category:Programmed cell death]] |
[[Category:Programmed cell death]] |
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{{Cell-biology-stub}} |
{{Cell-biology-stub}} |
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Revision as of 02:34, 27 May 2016
Karyorrhexis (from Greek κάρυον karyon, "kernel, seed or nucleus", and ῥῆξις rhexis, "bursting") is the destructive fragmentation of the nucleus of a dying cell[1] whereby its chromatin is distributed irregularly throughout the cytoplasm. It is usually preceded by pyknosis and can occur as a result of either programmed cell death (apoptosis), senescence, or necrosis.
In apoptosis, the cleavage of DNA is done by Ca2+ and Mg2+ -dependent endonucleases.
See also
References
- ^ Zamzami N, Kroemer G (1999). "Apoptosis: Condensed matter in cell death". Nature. 401 (127): 127–8. doi:10.1038/43591. PMID 10490018.
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