PIGK: Difference between revisions
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'''GPI-anchor transamidase''' is an [[enzyme]] that in humans is encoded by the ''PIGK'' [[gene]].<ref name="pmid9356492">{{cite journal | author = Yu J, Nagarajan S, Knez JJ, Udenfriend S, Chen R, Medof ME | title = The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase | journal = Proc Natl Acad Sci U S A | volume = 94 | issue = 23 | pages = 12580–5 | |
'''GPI-anchor transamidase''' is an [[enzyme]] that in humans is encoded by the ''PIGK'' [[gene]].<ref name="pmid9356492">{{cite journal | author = Yu J, Nagarajan S, Knez JJ, Udenfriend S, Chen R, Medof ME | title = The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase | journal = Proc Natl Acad Sci U S A | volume = 94 | issue = 23 | pages = 12580–5 |date=December 1997 | pmid = 9356492 | pmc = 25045 | doi =10.1073/pnas.94.23.12580 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PIGK phosphatidylinositol glycan anchor biosynthesis, class K| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10026| accessdate = }}</ref> |
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==Interactions== |
==Interactions== |
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PIGK has been shown to [[Protein-protein interaction|interact]] with [[PIGT]]<ref name=pmid12582175>{{cite journal |last=Ohishi |first=Kazuhito |authorlink= |coauthors=Nagamune Kisaburo, Maeda Yusuke, Kinoshita Taroh | |
PIGK has been shown to [[Protein-protein interaction|interact]] with [[PIGT]]<ref name=pmid12582175>{{cite journal |last=Ohishi |first=Kazuhito |authorlink= |coauthors=Nagamune Kisaburo, Maeda Yusuke, Kinoshita Taroh |date=April 2003 |title=Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge |journal=J. Biol. Chem. |volume=278 |issue=16 |pages=13959–67 |publisher= |location = United States| issn = 0021-9258| pmid = 12582175 |doi = 10.1074/jbc.M300586200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[GPAA1]].<ref name=pmid10793132>{{cite journal |last=Ohishi |first=K |authorlink= |coauthors=Inoue N, Maeda Y, Takeda J, Riezman H, Kinoshita T |date=May 2000 |title=Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins |journal=Mol. Biol. Cell |volume=11 |issue=5 |pages=1523–33 |publisher= |location = UNITED STATES| issn = 1059-1524| pmid = 10793132 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=14864 }}</ref><ref name=pmid12052837>{{cite journal |last=Vainauskas |first=Saulius |authorlink= |coauthors=Maeda Yusuke, Kurniawan Henry, Kinoshita Taroh, Menon Anant K |date=August 2002 |title=Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex |journal=J. Biol. Chem. |volume=277 |issue=34 |pages=30535–42 |publisher= |location = United States| issn = 0021-9258| pmid = 12052837 |doi = 10.1074/jbc.M205402200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> |
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==References== |
==References== |
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Revision as of 14:17, 28 January 2014
Template:PBB GPI-anchor transamidase is an enzyme that in humans is encoded by the PIGK gene.[1][2]
Interactions
PIGK has been shown to interact with PIGT[3] and GPAA1.[4][5]
References
- ^ Yu J, Nagarajan S, Knez JJ, Udenfriend S, Chen R, Medof ME (December 1997). "The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase". Proc Natl Acad Sci U S A. 94 (23): 12580–5. doi:10.1073/pnas.94.23.12580. PMC 25045. PMID 9356492.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ "Entrez Gene: PIGK phosphatidylinositol glycan anchor biosynthesis, class K".
- ^ Ohishi, Kazuhito (April 2003). "Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge". J. Biol. Chem. 278 (16). United States: 13959–67. doi:10.1074/jbc.M300586200. ISSN 0021-9258. PMID 12582175.
{{cite journal}}: Cite has empty unknown parameters:|laydate=,|laysummary=, and|laysource=(help); Unknown parameter|coauthors=ignored (|author=suggested) (help)CS1 maint: unflagged free DOI (link) - ^ Ohishi, K (May 2000). "Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins". Mol. Biol. Cell. 11 (5). UNITED STATES: 1523–33. ISSN 1059-1524. PMC 14864. PMID 10793132.
{{cite journal}}: Cite has empty unknown parameters:|laydate=,|laysummary=, and|laysource=(help); Unknown parameter|coauthors=ignored (|author=suggested) (help) - ^ Vainauskas, Saulius (August 2002). "Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex". J. Biol. Chem. 277 (34). United States: 30535–42. doi:10.1074/jbc.M205402200. ISSN 0021-9258. PMID 12052837.
{{cite journal}}: Cite has empty unknown parameters:|laydate=,|laysummary=, and|laysource=(help); Unknown parameter|coauthors=ignored (|author=suggested) (help)CS1 maint: unflagged free DOI (link)
Further reading
External links
- PIGK human gene location in the UCSC Genome Browser.
- PIGK human gene details in the UCSC Genome Browser.
 | This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it. |