NONMEM: Difference between revisions
Content deleted Content added
+URL |
-webarchive, URL update, +refs |
||
| Line 1: | Line 1: | ||
{{Orphan|date=December 2007}} |
{{Orphan|date=December 2007}} |
||
'''NONMEM''' is a software package developed at [[UCSF]] for |
'''NONMEM''' is a software package developed by Stuart L. Beal and Lewis B. Sheiner in the late 1970s at [[UCSF]] for [[Pharmacokinetics#Population pharmacokinetics|population pharmacokinetical modeling]].<ref name="PopPK1" /><ref name="PopPK2" /><ref name="PopPK3" /> Its name is an acronym for non-linear [[Mixed model|mixed effects modeling]] and has become the "gold standard", both in the pharmaceutical industry and academia. |
||
==References== |
|||
<div class='references-small'> |
|||
<references> |
|||
<ref name="PopPK1">{{cite journal | title = Evaluation of Methods for Estimating Population Pharmacokinetic Parameters I. Michaelis-Menten Model: Routine Clinical Pharmacokinetic Data | journal = Journal of Pharmacokinetics and Biopharmaceutics | date = 1980 | first = Lewis B. | last = Sheiner | coauthors = Stuart L. Beal | volume = 8 | issue = 6 | pages = 553–571 | id = {{doi | 10.1007/BF01060053}}}}</ref> |
|||
<ref name="PopPK2">{{cite journal | title = Evaluation of Methods for Estimating Population Pharmacokinetic Parameters II. Biexponential Model and Experimental Pharmacokinetic Data | journal = Journal of Pharmacokinetics and Biopharmaceutics | date = 1981 | first = Lewis B. | last = Sheiner | coauthors = Stuart L. Beal | volume = 9 | issue = 5 | pages = 635–651 | id = {{doi | 10.1007/BF01061030}}}}</ref> |
|||
<ref name="PopPK3">{{cite journal | title = Evaluation of Methods for Estimating Population Pharmacokinetic Parameters III. Monoexponential Model: Routine Clinical Pharmacokinetic Data | journal = Journal of Pharmacokinetics and Biopharmaceutics | date = 1983 | first = Lewis B. | last = Sheiner | coauthors = Stuart L. Beal | volume = 11 | issue = 3 | pages = 303–319 | id = {{doi | 10.1007/BF01061870}}}}</ref> |
|||
</references> |
|||
</div> |
|||
==External links== |
==External links== |
||
| ⚫ | |||
*[http://web.archive.org/web/20080508041958/http://c255.ucsf.edu/nonmem1.html Archived version on Wayback] |
|||
| ⚫ | |||
[[Category:Pharmacokinetics]] |
[[Category:Pharmacokinetics]] |
||
Revision as of 22:11, 1 April 2011
NONMEM is a software package developed by Stuart L. Beal and Lewis B. Sheiner in the late 1970s at UCSF for population pharmacokinetical modeling.[1][2][3] Its name is an acronym for non-linear mixed effects modeling and has become the "gold standard", both in the pharmaceutical industry and academia.
References
- ^ Sheiner, Lewis B. (1980). "Evaluation of Methods for Estimating Population Pharmacokinetic Parameters I. Michaelis-Menten Model: Routine Clinical Pharmacokinetic Data". Journal of Pharmacokinetics and Biopharmaceutics. 8 (6): 553–571. doi:10.1007/BF01060053.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help) - ^ Sheiner, Lewis B. (1981). "Evaluation of Methods for Estimating Population Pharmacokinetic Parameters II. Biexponential Model and Experimental Pharmacokinetic Data". Journal of Pharmacokinetics and Biopharmaceutics. 9 (5): 635–651. doi:10.1007/BF01061030.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help) - ^ Sheiner, Lewis B. (1983). "Evaluation of Methods for Estimating Population Pharmacokinetic Parameters III. Monoexponential Model: Routine Clinical Pharmacokinetic Data". Journal of Pharmacokinetics and Biopharmaceutics. 11 (3): 303–319. doi:10.1007/BF01061870.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help)
External links
- Product site Product site]
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |