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'''GPI-anchor transamidase''' is an [[enzyme]] that in humans is encoded by the ''PIGK'' [[gene]].<ref name="pmid9356492">{{cite journal | author = Yu J, Nagarajan S, Knez JJ, Udenfriend S, Chen R, Medof ME | title = The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase | journal = Proc Natl Acad Sci U S A | volume = 94 | issue = 23 | pages = 12580–5 | year = 1997 | month = Dec | pmid = 9356492 | pmc = 25045 | doi =10.1073/pnas.94.23.12580 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PIGK phosphatidylinositol glycan anchor biosynthesis, class K| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10026| accessdate = }}</ref>
'''GPI-anchor transamidase''' is an [[enzyme]] that in humans is encoded by the ''PIGK'' [[gene]].<ref name="pmid9356492">{{cite journal | author = Yu J, Nagarajan S, Knez JJ, Udenfriend S, Chen R, Medof ME | title = The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase | journal = Proc Natl Acad Sci U S A | volume = 94 | issue = 23 | pages = 12580–5 | year = 1997 | month = Dec | pmid = 9356492 | pmc = 25045 | doi =10.1073/pnas.94.23.12580 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PIGK phosphatidylinositol glycan anchor biosynthesis, class K| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10026| accessdate = }}</ref>

Revision as of 00:31, 22 December 2010

Template:PBB GPI-anchor transamidase is an enzyme that in humans is encoded by the PIGK gene.[1][2]

Template:PBB Summary

Interactions

PIGK has been shown to interact with PIGT[3] and GPAA1.[4][5]

References

  1. ^ Yu J, Nagarajan S, Knez JJ, Udenfriend S, Chen R, Medof ME (1997). "The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase". Proc Natl Acad Sci U S A. 94 (23): 12580–5. doi:10.1073/pnas.94.23.12580. PMC 25045. PMID 9356492. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. ^ "Entrez Gene: PIGK phosphatidylinositol glycan anchor biosynthesis, class K".
  3. ^ Ohishi, Kazuhito (2003). "Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge". J. Biol. Chem. 278 (16). United States: 13959–67. doi:10.1074/jbc.M300586200. ISSN 0021-9258. PMID 12582175. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link)
  4. ^ Ohishi, K (2000). "Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins". Mol. Biol. Cell. 11 (5). UNITED STATES: 1523–33. ISSN 1059-1524. PMC 14864. PMID 10793132. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: year (link)
  5. ^ Vainauskas, Saulius (2002). "Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex". J. Biol. Chem. 277 (34). United States: 30535–42. doi:10.1074/jbc.M205402200. ISSN 0021-9258. PMID 12052837. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link)

Further reading

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