Ent-kaurenoic acid oxidase: Difference between revisions
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{{Short description|Class of enzymes}} |
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{{Infobox enzyme |
{{Infobox enzyme |
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| Name = Ent-kaurenoic acid oxidase |
| Name = Ent-kaurenoic acid oxidase |
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| EC_number = 1.14.13.79 |
| EC_number = 1.14.13.79 |
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| CAS_number = 337507-95-6 |
| CAS_number = 337507-95-6 |
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| GO_code = |
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| IUBMB_EC_number = 1/14/13/79 |
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'''Ent-kaurenoic acid oxidase''' ({{EC number|1.14.13.79}}) is an [[enzyme]] with |
'''Ent-kaurenoic acid oxidase''' ({{EC number|1.14.13.79}}) is an [[enzyme]] with [[List of enzymes|systematic name]] ''ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating)''.<ref>{{cite journal | vauthors = Helliwell CA, Chandler PM, Poole A, Dennis ES, Peacock WJ | title = The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 98 | issue = 4 | pages = 2065–70 | date = February 2001 | pmid = 11172076 | pmc = 29382 | doi = 10.1073/pnas.041588998 | doi-access = free }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]] |
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: ent-kaur-16-en-19-oate + 3 NADPH + 3 H<sup>+</sup> + 3 O<sub>2</sub> <math>\rightleftharpoons</math> gibberellin A12 + 3 NADP<sup>+</sup> + 4 H<sub>2</sub>O (overall reaction) |
: ent-kaur-16-en-19-oate + 3 NADPH + 3 H<sup>+</sup> + 3 O<sub>2</sub> <math>\rightleftharpoons</math> gibberellin A12 + 3 NADP<sup>+</sup> + 4 H<sub>2</sub>O (overall reaction) |
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== External links == |
== External links == |
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* {{MeshName|Ent-kaurenoic+acid+oxidase}} |
* {{MeshName|Ent-kaurenoic+acid+oxidase}} |
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{{Dioxygenases}} |
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{{Enzymes}} |
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{{Portal bar|Biology|border=no}} |
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[[Category:EC 1.14.13]] |
[[Category:EC 1.14.13]] |
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{{Enzyme-stub}} |
Latest revision as of 13:58, 26 August 2023
Ent-kaurenoic acid oxidase | |||||||||
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Identifiers | |||||||||
EC no. | 1.14.13.79 | ||||||||
CAS no. | 337507-95-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Ent-kaurenoic acid oxidase (EC 1.14.13.79) is an enzyme with systematic name ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating).[1] This enzyme catalyses the following chemical reaction
- ent-kaur-16-en-19-oate + 3 NADPH + 3 H+ + 3 O2 gibberellin A12 + 3 NADP+ + 4 H2O (overall reaction)
- (1a) ent-kaur-16-en-19-oate + NADPH + H+ + O2 ent-7alpha-hydroxykaur-16-en-19-oate + NADP+ + H2O
- (1b) ent-7alpha-hydroxykaur-16-en-19-oate + NADPH + H+ + O2 gibberellin A12 aldehyde + NADP+ + 2 H2O
- (1c) gibberellin A12 aldehyde + NADPH + H+ + O2 gibberellin A12 + NADP+ + H2O
Ent-kaurenoic acid oxidase requires cytochrome P450.
References
[edit]- ^ Helliwell CA, Chandler PM, Poole A, Dennis ES, Peacock WJ (February 2001). "The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway". Proceedings of the National Academy of Sciences of the United States of America. 98 (4): 2065–70. doi:10.1073/pnas.041588998. PMC 29382. PMID 11172076.
External links
[edit]- Ent-kaurenoic+acid+oxidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)